Glycomet 500 (Metformin 500mg): Complete Diabetes Guide (2026)

Last reviewed by Komal Sharma, Registered Pharmacist · Rajdhani Medicos · Drug License RLF21DL2025003179

With over 10 crore Indians living with Type 2 diabetes, Metformin — sold as Glycomet 500 — is the single most prescribed diabetes medicine in the country. If you or a family member was recently diagnosed, this guide explains exactly how Glycomet 500 works, how to take it correctly, and how to never miss a refill.

What is Glycomet 500?

Glycomet 500 is a Metformin Hydrochloride 500 mg tablet manufactured by USV Pharmaceuticals. It belongs to a class of medicines called biguanides and is the recommended first-line treatment for Type 2 diabetes worldwide.

Key facts:

• Active ingredient: Metformin Hydrochloride 500 mg
• Manufacturer: USV Pvt Ltd
• Class: Biguanide (anti-diabetic)
• Pack: Strip of 10 / 15 / 20 tablets
• Price in India: ₹14-30 per strip
• Schedule: H (Prescription required)

How Does Glycomet 500 Control Blood Sugar?

Metformin works in three ways:

1. Reduces glucose production — Stops your liver from releasing too much sugar into the blood.
2. Improves insulin sensitivity — Helps your body's cells respond better to insulin, so they absorb more sugar.
3. Slows sugar absorption — Reduces the amount of glucose absorbed from food in your intestines.

Unlike some diabetes medicines, Metformin does not cause weight gain and has a low risk of hypoglycemia (dangerously low blood sugar) when used alone.

Uses of Glycomet 500

1. Type 2 Diabetes (primary use)

Controls blood sugar in adults and children (10+) with Type 2 diabetes, alongside diet and exercise.

2. Prediabetes

Often prescribed to prevent progression from prediabetes to full diabetes.

3. PCOS (Polycystic Ovary Syndrome)

Helps women with PCOS improve insulin resistance and restore regular ovulation.

4. Weight Management in Diabetics

May support modest weight loss in overweight diabetic patients.

Glycomet 500 Dosage — How to Take It

Always follow your doctor's prescription. General guidelines:

Starting dose

• 1 tablet (500 mg) once or twice daily, with meals
• Doctor gradually increases based on blood sugar response

Maintenance dose

• Usually 500-1000 mg twice daily (with breakfast and dinner)
• Maximum: 2000-2500 mg per day

The golden rule: ALWAYS take with food

Metformin can upset your stomach. Taking it during or right after meals dramatically reduces nausea, diarrhea, and cramps.

Extended-release version (Glycomet SR / GP)

If you get stomach issues, ask your doctor about Glycomet SR (sustained release) — taken once daily, gentler on the stomach.

Glycomet 500 Side Effects

Common (usually settle in 1-2 weeks)

• Nausea
• Diarrhea
• Stomach cramps
• Metallic taste in mouth
• Loss of appetite

Tip: These reduce significantly when you take Metformin WITH food and start with a low dose.

Long-term use

• Vitamin B12 deficiency — Get your B12 checked yearly. Deficiency causes fatigue, tingling in hands/feet.

Rare but serious (seek immediate help)

• Lactic acidosis — Very rare. Symptoms: extreme tiredness, muscle pain, difficulty breathing, unusual sleepiness. More likely in people with kidney/liver disease.

Call our pharmacist at +91 7982544355 if you experience any unusual symptoms.

Foods & Habits to Combine with Glycomet

Medicine alone won't control diabetes. Combine Glycomet with:

1. Low glycemic index foods — Whole grains (bajra, jowar, oats), legumes, vegetables
2. Avoid — White rice, maida, sugar, sweets, fried food, soft drinks
3. Portion control — Smaller, frequent meals keep blood sugar steady
4. 30 min daily walk — Exercise improves insulin sensitivity dramatically
5. Stay hydrated — Drink 2-3 litres of water
6. Monitor blood sugar — Keep a glucometer at home (fasting & post-meal)
7. Regular HbA1c test — Every 3 months (target: below 7%)

Never Run Out — Diabetes Refill Made Easy

Missing diabetes medicine even for a few days can spike your blood sugar dangerously. That's why Rajdhani Medicos offers auto-refill subscriptions for chronic medicines:

• Save 10% on every monthly refill
• Automatic reminders before you run out
• Same-day delivery in Delhi
• Pause or cancel anytime

Set up your Glycomet refill →

Buy Glycomet 500 Online in Delhi

Rajdhani Medicos delivers genuine Glycomet 500 (USV) with verified batches across Delhi:

• South Delhi — Sarita Vihar, Okhla, Lajpat Nagar, GK, Defence Colony, Kalkaji
• West Delhi — Dwarka, Janakpuri, Rajouri Garden
• East Delhi — Mayur Vihar, Preet Vihar, Laxmi Nagar
• North Delhi — Model Town, Civil Lines
• NCR — Noida, Gurgaon, Faridabad, Ghaziabad

Free delivery above ₹499 · COD available · Upload prescription for pharmacist verification

Order Glycomet 500 Now →

Frequently Asked Questions

Can I stop Glycomet once my sugar is normal?

No — never stop diabetes medicine without your doctor's advice. Your sugar is normal because of the medicine. Stopping will make it rise again.

Is Glycomet 500 safe for long-term use?

Yes. Metformin is one of the safest, most studied diabetes medicines and is used for decades safely. Just monitor B12 levels yearly.

When is the best time to take Glycomet?

With or right after meals — usually breakfast and dinner. This minimizes stomach side effects.

Does Glycomet cause weight loss?

It may cause modest weight loss or weight stability, unlike some other diabetes medicines that cause weight gain.

Can I take Glycomet during pregnancy?

Metformin is sometimes used in pregnancy (especially for PCOS or gestational diabetes) but only under specialist supervision. Consult your doctor.

What if I miss a dose?

Take it with your next meal. Never double up. If you miss frequently, set up auto-refill reminders so you never run out.

Can diabetics get same-day medicine delivery in Delhi?

Yes — Rajdhani Medicos delivers diabetes medicines same-day within Delhi. Set up a subscription for automatic monthly refills at 10% off.

What is the normal blood sugar range?

• Fasting: 70-100 mg/dL (normal), 100-125 (prediabetes), 126+ (diabetes)
• Post-meal (2 hrs): below 140 mg/dL (normal)
• HbA1c: below 5.7% (normal), 5.7-6.4% (prediabetes), 6.5%+ (diabetes)

When to See a Doctor

Contact your doctor or call us at +91 7982544355 if:

• Blood sugar stays high despite medicine
• You have symptoms of low blood sugar (shaking, sweating, confusion)
• Persistent vomiting or diarrhea
• Signs of lactic acidosis (muscle pain, breathlessness, extreme fatigue)
• You develop tingling/numbness (possible B12 deficiency)

Disclaimer: This article is for informational purposes only and does not replace professional medical advice. Glycomet 500 is a prescription medicine — never start, stop, or change your dose without consulting a doctor.

About the reviewer: Komal Sharma is a Registered Pharmacist with the Delhi Pharmacy Council, and consulting pharmacist for Rajdhani Medicos.

Rajdhani Medicos — Licensed online pharmacy serving Delhi. Drug License RLF21DL2025003179. GSTIN 07KXQPK3422R1ZJ.